21.10.2012, 17:30
Infect Immun. 2003 Jul;71(7):3979-87.
Borrelia burgdorferi-induced tolerance as a model of persistence via immunosuppression
Diterich I, Rauter C, Kirschning CJ, Hartung T.
Biochemical Pharmacology, Faculty of Biology, University of Konstanz, Konstanz, Germany.
Abstract
If left untreated, infection with Borrelia burgdorferi sensu lato may lead to chronic Lyme borreliosis. It is still unknown how this pathogen manages to persist in the host in the presence of competent immune cells. It was recently reported that Borrelia suppresses the host's immune response, thus perhaps preventing the elimination of the pathogen (I. Diterich, L. Härter, D. Hassler, A. Wendel, and T. Hartung, Infect. Immun. 69:687-694, 2001)
PMID: 12819085 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/pubmed/12819085
Borrelia burgdorferi-induced tolerance as a model of persistence via immunosuppression
Diterich I, Rauter C, Kirschning CJ, Hartung T.
Biochemical Pharmacology, Faculty of Biology, University of Konstanz, Konstanz, Germany.
Abstract
If left untreated, infection with Borrelia burgdorferi sensu lato may lead to chronic Lyme borreliosis. It is still unknown how this pathogen manages to persist in the host in the presence of competent immune cells. It was recently reported that Borrelia suppresses the host's immune response, thus perhaps preventing the elimination of the pathogen (I. Diterich, L. Härter, D. Hassler, A. Wendel, and T. Hartung, Infect. Immun. 69:687-694, 2001)
PMID: 12819085 [PubMed - indexed for MEDLINE]
http://www.ncbi.nlm.nih.gov/pubmed/12819085
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